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PATENT COOPERATION TREATY 



From the 

"INTERNATIONAL SEARCHING AUTHORITY 



To: 



REC'D fl 3 p EB 200 g 



WIPO 



see form PCT/iSA/220 



PCT 



PCT 



WRITTEN OPINION OF THE 
INTERNATIONAL SEARCHING AUTHORITY 
(PCT Rule43b/s.1) 



Applicant's or agent's file reference 

see form PCTyiSA/220 



International application No. 
PCT1L2005/OG1078 



Date of mailing 

(day/monlhfyear) see form PCT7ISAi210 (second sheet) 



FOR FURTHER ACTION 

See paragraph 2 below 



International filing date (day/monih/year) 
11.10.2005 



International Patent Classification (IPC) or both national classification and IPC 
G01N15/14, B01L3/00, C12M1/22 



Priority date (day/month/year) 
18.10.2004 



Applicant 

MOLECULAR CYTOMICS LTD. 



This opinion contains indications relating to the following items: 



El Box No. I 

□ Box No. 11 

□ Box No. HI 

□ Box No. IV 
S Box No. V 

□ Box No. VI 

□ Box No. VII 

□ Box No. VIII 



Basis of the opinion 
Priority 

Non-establishment of opinion with regard to novelty, inventive step and industrial applicability 
Lack of unity of invention 

J^SS^IS 11 * Und / r R V ,e 435/51 (a)(l) With regard to nove *y' inventive step or industrial 
applicability; citations and explanations supporting such statement 

Certain documents cited 

Certain defects in the international application 

Certain observations on the international application 



2. FURTHER ACTION 

If a demand for international preliminary examination is made, this opinbn will usuallv be consider* to h« a 
wntten opinion of the International Preliminary Examining Authoritv ffirSft^S . u 
the applicant chooses an Authority other tharf this one tote W 

2^ 



3. 



If this opinion is, as provided above, considered to be a written oDinion of the IPPA tho IZ^w^TiTT^Z'Ji 

SKtaSi^f t *™W «*« appropriate" ^^Lttffit, 
XhlUTex*r G esS ma " ,n9 ° f ^ PC1ASA/220 ° r ™™ *• expiration of 22 months iffiSMJS* 

For further options, see Form PCT/ISA/220. 

For further details, see notes to Form PCT/ISA220. 



Name and mailing address of the ISA: 



J 



European Patent Office 
D-80298 Munich 

Tel. +49 89 2399 - 0 Tx: 523656 epmu d 
Fax: +49 89 2399 - 4465 



Authorized Officer 

Tiede, R 

Telephone No. +49 89 2399-1090 



Form (PCT/ISAC37) (Cover Sheet) (January 2004) 



Best Available Copy 



J?5EJ? N OPIN,ON OF THE International application No, 

INTERNATIONAL SEARCHING AUTHORITY PCT/IL2005/001 078 



Box No. I Basis of the opinion 

1 . With regard to the language, this opinion has been established on the basis of the international application in 
the language in which it was filed, unless otherwise indicated under this item. 

□ This opinion has been established on the basis of a translation from the original language into the following 
language , which is the language of a translation furnished for the purposes of international search 
(under Rules 12.3 and 23.1(b)). 

2. With regard to any nucleotide and/or amino acid sequence disclosed in the international application and 
necessary to the claimed invention, this opinion has been established on the basis of: 

a. type of material: 

□ a sequence listing 

□ table(s) related to the sequence listing 

b. format of material: 

□ in written format 

□ in computer readable form 

c. time of filing/furnishing: 

□ contained in the international application as filed. 

□ filed together with the international application in computer readable form. 

□ furnished subsequently to this Authority for the purposes of search. 

3. □ In addition, in the case that more than one version or copy of a sequence listing andfor table relating thereto 

has been filed or furnished, the required statements that the information in the subsequent or additional 
copies is identical to that in the application as filed or does not go beyond the application as filed as 
appropriate, were furnished. 

4. Additional comments: 



Form PCTMSA/237 (January 2004) 



Best Available Copy 



WRITTEN OPINION OF THE 
INTERNATIONAL SEARCHING AUTHORITY 



International application No 
PCT/IL2005A)01078 




Inventive step (IS) 
Industrial applicability (IA) 

2. Citations and explanations 
see separate sheet 



Yes: Claims 
No: Claims 

Yes: Claims 
No: Claims 

Yes: Claims 
No: Claims 



1-49 

1-49 
1-49 



Form PCT4SA/237 (January 2004)